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Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon.

The second of three short upstream open reading frames (uORF2) in the transcript leader of the human cytomegalovirus gp48 (gpUL4) virion glycoprotein gene inhibits downstream translation approximately 10-fold. Remarkably, this inhibition depends on the amino acid coding information of uORF2. In the...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Cao, J, Geballe, A P
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.1030-1036.1995
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