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Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon.

The second of three short upstream open reading frames (uORF2) in the transcript leader of the human cytomegalovirus gp48 (gpUL4) virion glycoprotein gene inhibits downstream translation approximately 10-fold. Remarkably, this inhibition depends on the amino acid coding information of uORF2. In the...

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Detalhes bibliográficos
Main Authors: Cao, J, Geballe, A P
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188673/
https://ncbi.nlm.nih.gov/pubmed/7815480
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