Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts.

The simian virus 40 large T antigen immortalizes growing primary cells in culture. In addition, this viral oncoprotein cooperates with an activated ras protein to produce dense foci on monolayers of rat embryo fibroblasts (REF). The relationship between independent immortalization and cooperative tr...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Cavender, J F, Conn, A, Epler, M, Lacko, H, Tevethia, M J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1995
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.923-934.1995
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