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The primary structure of the prion protein influences the distribution of abnormal prion protein in the central nervous system.

We immunohistochemically examined tissue sections from patients with prion protein (PrP) polymorphism using hydrolytic autoclaving enhancement. Abnormal PrP accumulations could be classified into plaque formations (plaque-type) and the diffuse gray matter stainings including synaptic structures (syn...

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Autors principals: Kitamoto, T., Doh-ura, K., Muramoto, T., Miyazono, M., Tateishi, J.
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886604/
https://ncbi.nlm.nih.gov/pubmed/1353945
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