A novel translational regulation function for the simian virus 40 large-T antigen gene.

Cells use the interferon-induced, double-stranded-RNA-dependent protein kinase PKR as a defense against virus infections. Upon activation, PKR phosphorylates and thereby inactivates the protein synthesis initiation factor eIF-2, resulting in the cessation of protein synthesis. Viruses have evolved v...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Rajan, P, Swaminathan, S, Zhu, J, Cole, C N, Barber, G, Tevethia, M J, Thimmapaya, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.785-795.1995
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!