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Accumulation of amyloid precursor protein in neurons after intraventricular injection of colchicine.

To study a possible relationship between inhibition of axonal flow and amyloidogenesis, the authors examined amyloid precursor protein (APP) immunoreactivity in rat brain treated with colchicine. After intraventricular injection of colchicine, the proximal axons of exposed neurons became swollen and...

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Detalhes bibliográficos
Main Authors: Shigematsu, K., McGeer, P. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886374/
https://ncbi.nlm.nih.gov/pubmed/1373270
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