Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.

The vaccinia virus (VV) E3L gene, which encodes a potent inhibitor of the interferon (IFN)-induced, double-stranded RNA (dsRNA)-dependent protein kinase, PKR, is thought to be involved in the IFN-resistant phenotype of VV. The E3L gene products, p25 and p20, act as inhibitors of PKR, presumably by b...

Celý popis

Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Beattie, E, Denzler, K L, Tartaglia, J, Perkus, M E, Paoletti, E, Jacobs, B L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.499-505.1995
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!