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Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient mice.

Mutants of mammalian reoviruses, enteric double-stranded-RNA-containing viruses that spread systemically after primary replication in intestinal tissue, have been extensively studied as models of viral pathogenesis. While reovirus serotype 3 strain Dearing (T3D) causes acute encephalitis in newborn...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Haller, B L, Barkon, M L, Li, X Y, Hu, W M, Wetzel, J D, Dermody, T S, Virgin, H W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7745749/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.6.3933-3937.1995
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