Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient mice.

Mutants of mammalian reoviruses, enteric double-stranded-RNA-containing viruses that spread systemically after primary replication in intestinal tissue, have been extensively studied as models of viral pathogenesis. While reovirus serotype 3 strain Dearing (T3D) causes acute encephalitis in newborn...

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Détails bibliographiques
Auteurs principaux: Haller, B L, Barkon, M L, Li, X Y, Hu, W M, Wetzel, J D, Dermody, T S, Virgin, H W
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC189121/
https://ncbi.nlm.nih.gov/pubmed/7745749
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