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Load-dependent mechanism of nonmuscle myosin 2

Loads on molecular motors regulate and coordinate their function. In a study that directly measures properties of internally strained myosin 2 heads bound to actin, we find that human nonmuscle myosins 2A and 2B show marked load-dependent changes in kinetics of ADP release but not in nucleotide bind...

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Detalhes bibliográficos
Main Authors: Kovács, Mihály, Thirumurugan, Kavitha, Knight, Peter J., Sellers, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885822/
https://ncbi.nlm.nih.gov/pubmed/17548820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701181104
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