Loading...
Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C
Despite a generic, highly conserved motor domain, ATP turnover kinetics and their activation by F-actin vary greatly between myosin-2 isoforms. Here, we present a 2.25 Å pre-powerstroke state (ADP⋅VO(4)) crystal structure of the human nonmuscle myosin-2C motor domain, one of the slowest myosins char...
Saved in:
| Published in: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
eLife Sciences Publications, Ltd
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749951/ https://ncbi.nlm.nih.gov/pubmed/29256864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32742 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|