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Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

Nonmusclemyosin 2 (NM-2) powers cell motility and tissue morphogenesis by assembling into bipolar filaments that interact with actin. Although the enzymatic properties of purified NM-2 motor fragments have been determined, the emergent properties of filament ensembles are unknown. Using single myosi...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Melli, Luca, Billington, Neil, Sun, Sara A, Bird, Jonathan E, Nagy, Attila, Friedman, Thomas B, Takagi, Yasuharu, Sellers, James R
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829915/
https://ncbi.nlm.nih.gov/pubmed/29419377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32871
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