Inhibition of the Tissue Factor-Thrombin Pathway Limits Infarct Size after Myocardial Ischemia-Reperfusion Injury by Reducing Inflammation

Functional inhibition of tissue factor (TF) has been shown to improve coronary blood flow after myocardial ischemia/reperfusion (I/R) injury. TF initiates the coagulation protease cascade, resulting in the generation of the serine protease thrombin and fibrin deposition. Thrombin can also contribute...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Erlich, Jonathan H., Boyle, Edward M., Labriola, Joanne, Kovacich, J. Craig, Santucci, Richard A., Fearns, Colleen, Morgan, Elizabeth N., Yun, Wang, Luther, Thomas, Kojikawa, Osamu, Martin, Thomas R., Pohlman, Timothy H., Verrier, Edward D., Mackman, Nigel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2000
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885771/
https://ncbi.nlm.nih.gov/pubmed/11106558
Tagiau: Ychwanegu Tag
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