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Biochemical and cellular characteristics of the 3′ → 5′ exonuclease TREX2

TREX2 is an autonomous nonprocessive 3′ → 5′ exonuclease, suggesting that it maintains genome integrity. To investigate TREX2's biochemical and cellular properties, we show that endogenous TREX2 is expressed widely in mouse tissues and human cell lines. Unexpectedly, endogenous human TREX2 is p...

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Detalhes bibliográficos
Main Authors: Chen, Ming-Jiu, Ma, Sheng-Mei, Dumitrache, Lavinia C., Hasty, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885668/
https://ncbi.nlm.nih.gov/pubmed/17426129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm151
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