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Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Chromosome instability and aneuploidy are hallmarks of cancer, but it is not clear how changes in the chromosomal content of a cell contribute to the malignant phenotype. Previously we have shown that we can readily isolate highly proliferative tumor cells and their revertants from highly invasive t...

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Hlavní autoři: Gao, ChongFeng, Furge, Kyle, Koeman, Julie, Dykema, Karl, Su, Yanli, Cutler, Mary Lou, Werts, Adam, Haak, Pete, Vande Woude, George F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885616/
https://ncbi.nlm.nih.gov/pubmed/17517657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700631104
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