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Cancer-Type Regulation of MIG-6 Expression by Inhibitors of Methylation and Histone Deacetylation
Epigenetic silencing is one of the mechanisms leading to inactivation of a tumor suppressor gene, either by DNA methylation or histone modification in a promoter regulatory region. Mitogen inducible gene 6 (MIG-6), mainly known as a negative feedback inhibitor of the epidermal growth factor receptor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373526/ https://ncbi.nlm.nih.gov/pubmed/22701735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038955 |
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