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Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation

A deficiency of mitogen-inducible gene-6 (Mig-6) in mice leads to the development of an early-onset, osteoarthritis (OA)-like disorder in multiple synovial joints, underlying its importance in maintaining joint homeostasis. Here we determined what joint tissues Mig-6 is expressed in and what role ch...

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Detalhes bibliográficos
Main Authors: Staal, Ben, Williams, Bart O., Beier, Frank, Vande Woude, George F., Zhang, Yu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932925/
https://ncbi.nlm.nih.gov/pubmed/24550287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400744111
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