NRAS mutation causes a human autoimmune lymphoproliferative syndrome

The p21 RAS subfamily of small GTPases, including KRAS, HRAS, and NRAS, regulates cell proliferation, cytoskeletal organization, and other signaling networks, and is the most frequent target of activating mutations in cancer. Activating germline mutations of KRAS and HRAS cause severe developmental...

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Detalhes bibliográficos
Main Authors: Oliveira, João B., Bidère, Nicolas, Niemela, Julie E., Zheng, Lixin, Sakai, Keiko, Nix, Cynthia P., Danner, Robert L., Barb, Jennifer, Munson, Peter J., Puck, Jennifer M., Dale, Janet, Straus, Stephen E., Fleisher, Thomas A., Lenardo, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885609/
https://ncbi.nlm.nih.gov/pubmed/17517660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702975104
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