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p53 status dictates responses of B lymphomas to monotherapy with proteasome inhibitors

The proapoptotic function of p53 is thought to underlie most anticancer modalities and is also activated in response to oncogenic insults, such as overexpression of the Myc oncoprotein. Here we generated tractable B lymphomas using retroviral transduction of the MYC oncogene into hematopoietic cells...

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Bibliografske podrobnosti
Main Authors: Yu, Duonan, Carroll, Martin, Thomas-Tikhonenko, Andrei
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885530/
https://ncbi.nlm.nih.gov/pubmed/17284530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-050294
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