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Adoptive transfer of tumor-primed, in vitro–activated, CD4(+) T effector cells (T(E)s) combined with CD8(+) T(E)s provides intratumoral T(E) proliferation and synergistic antitumor response
The importance of CD4(+) Th1 cells during the effector phase of the antitumor response has been overshadowed by emphasis on CD8(+) cytotoxic T lymphocytes (CTLs). To determine their respective functions, we purified antigen-primed T cells from tumor-draining lymph nodes and separately activated CD4(...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885514/ https://ncbi.nlm.nih.gov/pubmed/17284532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-045245 |
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