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Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability
Karyotypic abnormalities in cultured embryonic stem cells (ESCs), especially near-diploid aneuploidy, are potential obstacles to ESC use in regenerative medicine. Events causing chromosomal abnormalities in ESCs may be related to events in tumor cells causing chromosomal instability (CIN) in human d...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885509/ https://ncbi.nlm.nih.gov/pubmed/17289813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-054247 |
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