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Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal

BACKGROUND: Despite their distinct origins, human embryonic stem (hES) and embryonic carcinoma (hEC) cells share a number of similarities such as surface antigen expression, growth characteristics, the ability to either self-renew or differentiate, and control of the undifferentiated state by the sa...

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Detalhes bibliográficos
Main Authors: Greber, Boris, Lehrach, Hans, Adjaye, James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885259/
https://ncbi.nlm.nih.gov/pubmed/17506876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-7-46
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