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FGF Signalling in the Self-Renewal of Colon Cancer Organoids

The progression of colorectal cancer (CRC) is supposedly driven by cancer stem cells (CSC) which are able to self-renew and simultaneously fuel bulk tumour mass with highly proliferative and differentiated tumour cells. However, the CSC-phenotype in CRC is unstable and dependent on environmental cue...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Otte, Jörg, Dizdar, Levent, Behrens, Bianca, Goering, Wolfgang, Knoefel, Wolfram T., Wruck, Wasco, Stoecklein, Nikolas H., Adjaye, James
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874569/
https://ncbi.nlm.nih.gov/pubmed/31758153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53907-7
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