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Incorporation of a lambda phage recombination system and EGFP detection to simplify mutagenesis of Herpes simplex virus bacterial artificial chromosomes

BACKGROUND: Targeted mutagenesis of the herpesvirus genomes has been facilitated by the use of bacterial artificial chromosome (BAC) technology. Such modified genomes have potential uses in understanding viral pathogenesis, gene identification and characterization, and the development of new viral v...

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Bibliografske podrobnosti
Main Authors: Schmeisser, Falko, Weir, Jerry P
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885250/
https://ncbi.nlm.nih.gov/pubmed/17501993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-22
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