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Incorporation of a lambda phage recombination system and EGFP detection to simplify mutagenesis of Herpes simplex virus bacterial artificial chromosomes

BACKGROUND: Targeted mutagenesis of the herpesvirus genomes has been facilitated by the use of bacterial artificial chromosome (BAC) technology. Such modified genomes have potential uses in understanding viral pathogenesis, gene identification and characterization, and the development of new viral v...

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Библиографические подробности
Главные авторы: Schmeisser, Falko, Weir, Jerry P
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885250/
https://ncbi.nlm.nih.gov/pubmed/17501993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-22
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