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Incorporation of a lambda phage recombination system and EGFP detection to simplify mutagenesis of Herpes simplex virus bacterial artificial chromosomes

<p>Abstract</p> <p>Background</p> <p>Targeted mutagenesis of the herpesvirus genomes has been facilitated by the use of bacterial artificial chromosome (BAC) technology. Such modified genomes have potential uses in understanding viral pathogenesis, gene identification a...

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Auteurs principaux: Weir Jerry P, Schmeisser Falko
Format: Artigo
Langue:Inglês
Publié: BMC 2007-05-01
Collection:BMC Biotechnology
Accès en ligne:http://www.biomedcentral.com/1472-6750/7/22
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