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Two cases of thiopurine methyltransferase (TPMT) deficiency – a lucky save and a near miss with azathioprine

BACKGROUND: The association between thiopurine methyltransferase (TPMT) deficiency and myelosuppression with azathioprine is well recognized. Two cases are presented that illustrate the very different outcomes that may occur with azathioprine in patients with TPMT deficiency, which affects 0.3–0.6%...

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Autori principali: Gardiner, Sharon J, Gearry, Richard B, Barclay, Murray L, Begg, Evan J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885160/
https://ncbi.nlm.nih.gov/pubmed/16995868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02474.x
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