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The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1 (C3435T) polymorphisms and gender on the urinary excretion of the metabolites of the H(1)-receptor antihistamine ebastine: a pilot study
AIMS: To determine the effect of gender and the genetic polymorphisms of CYP2J2, CYP3A4, CYP3A5 and MDR1 on the urinary excretion of the H(1) antihistamine ebastine in healthy subjects. METHODS: Eighty-nine Caucasians were studied. The presence of polymorphisms in genes known to be involved in ebast...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885094/ https://ncbi.nlm.nih.gov/pubmed/16842392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02578.x |
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