Biological interactions of CYP2C19 genotypes with CYP3A4*18, CYP3A5*3, and MDR1-3435 in living donor liver transplantation recipients

BACKGROUND: Polymorphisms in CYP2C19 are related to the metabolic oxidation of drugs to varying degrees. The CYP3A4*18, CYP3A5*3, and MDR1-3435 variant alleles are very important, particularly in tacrolimus metabolism in organ transplant rejection. AIM: The aim of this study is o explore possible in...

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Bibliografske podrobnosti
Main Authors: Chiu, King-Wah, Hu, Tsung-Hui, Nakano, Toshiaki, Chen, Kuang-Den, Lai, Chia-Yun, Hsu, Li-Wen, Tseng, Hui-Peng, Chiu, Ho-Ching, Cheng, Yu-Fan, Goto, Shigeru, Chen, Chao-Long
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643843/
https://ncbi.nlm.nih.gov/pubmed/23617933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-1440-2-6
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