Population pharmacokinetics of tipifarnib in healthy subjects and adult cancer patients

AIMS: To characterize the population pharmacokinetics of tipifarnib. METHODS: A total of 1083 subjects treated orally with a solution, capsule or tablet formulations of tipifarnib, given as a single dose or as multiple twice-daily doses (range 25–1300 mg) were combined with data from 1, 2 and 24 h i...

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Main Authors: Perez-Ruixo, Juan Jose, Piotrovskij, Vladimir, Zhang, Steven, Hayes, Siobhan, Porre, Peter De, Zannikos, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2006
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885079/
https://ncbi.nlm.nih.gov/pubmed/16842381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02615.x
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