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Prediction of drug clearance in children from adults: a comparison of several allometric methods

AIM: In recent years with the advent of paediatric exclusivity and requirements to conduct clinical studies in children, the current emphasis is to find a safe and efficacious dose of a drug in children. It has been suggested that one can predict the clearance of a drug in children according to the...

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Autor principal: Mahmood, Iftekhar
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885056/
https://ncbi.nlm.nih.gov/pubmed/16669848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02622.x
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