Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals

AIMS: To investigate the pharmacokinetics and the pharmacodynamic effects in dorsal hand veins of the neurokinin-1 receptor antagonist SLV317. METHODS: In a randomized, double-blind, placebo-controlled cross-over study 19 healthy men received a single oral dose of SLV317 or placebo. Blood samples we...

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Detalhes bibliográficos
Main Authors: Hesse, Christiane, Luntz, Steffen P, Siedler, Heike, Unnebrink, Kristina, Mikus, Gerd, de Bruijn, Marianne, Zondag, Edu, de Vries, Michiel, Seibert-Grafe, Monika, Haefeli, Walter E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Pharmacokinetics & Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885038/
https://ncbi.nlm.nih.gov/pubmed/16542202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02590.x
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