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Within- and between- subject variability in methadone pharmacokinetics and pharmacodynamics in methadone maintenance subjects
AIMS: To investigate within- and between-subject variability of the pharmacodynamics and pharmacokinetics of (R)- and (S)-methadone in methadone maintenance subjects at steady-state. METHODS: Six non-holder subjects were studied on three occasions at 7–16 day intervals; doses (20–170 mg/day) remaine...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Blackwell Science Inc
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884832/ https://ncbi.nlm.nih.gov/pubmed/16187972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02464.x |
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