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Effects of grapefruit juice on the absorption of levothyroxine

AIMS: Our aim was to study the effect of grapefruit juice on the pharmacokinetics of levothyroxine. METHODS: In a randomized cross-over study with two phases, 10 healthy subjects ingested 200 ml grapefruit juice or water (control) three times daily for 2 days. On day 3, a single 600 µg dose of levot...

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Bibliografiske detaljer
Main Authors: Lilja, Jari J, Laitinen, Kalevi, Neuvonen, Pertti J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884777/
https://ncbi.nlm.nih.gov/pubmed/16120075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02433.x
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