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The use of pharmacokinetic and pharmacodynamic data in the assessment of drug safety in early drug development

The pharmaceutical industry continues to look for ways to reduce drug candidate attrition throughout the drug discovery and development process. A significant cause of attrition is due to safety issues arising either as a result of animal toxicity testing or in the clinical programme itself. A facto...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Walker, D K
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884636/
https://ncbi.nlm.nih.gov/pubmed/15563358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02194.x
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