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The use of pharmacokinetic and pharmacodynamic data in the assessment of drug safety in early drug development
The pharmaceutical industry continues to look for ways to reduce drug candidate attrition throughout the drug discovery and development process. A significant cause of attrition is due to safety issues arising either as a result of animal toxicity testing or in the clinical programme itself. A facto...
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2004
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884636/ https://ncbi.nlm.nih.gov/pubmed/15563358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02194.x |
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