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Pharmacokinetics of levosimendan and its circulating metabolites in patients with heart failure after an extended continuous infusion of levosimendan

AIMS: The purpose of the study was to characterize the pharmacokinetics of levosimendan and its metabolites OR-1855 and OR-1896 in patients with congestive heart failure. METHODS: Levosimendan was administered as a continuous intravenous infusion for 7 days. Twelve subjects received the drug at an i...

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Hlavní autoři: Antila, Saila, Kivikko, Matti, Lehtonen, Lasse, Eha, Jaan, Heikkilä, Aira, Pohjanjousi, Pasi, Pentikäinen, Pertti J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884479/
https://ncbi.nlm.nih.gov/pubmed/15025738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2003.02043.x
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