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Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females

AIMS: To investigate the influence of St. John's wort (SJW) on CYP3A4, CYP1A2, CYP2D6, N-acetyltransferase 2 (NAT2), and xanthine oxidase (XO) activities in healthy males and females. METHODS: Eight males and eight females were treated with SJW extract (3 × 300 mg day(−1)) for 14 days. Assessme...

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Detalhes bibliográficos
Main Authors: Wenk, Markus, Todesco, Liliane, Krähenbühl, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884478/
https://ncbi.nlm.nih.gov/pubmed/15025748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2003.02049.x
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