Lataa...
Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic–pharmacodynamic data
AIMS: To describe the population pharmacokinetic–pharmacodynamic relationship between darifenacin (UK-88,525) and its hydroxylated metabolite (UK-148,993), and the reduction in salivary flow (SF, a M(3)-mediated response). This enabled an estimation of the in vivo potency of the metabolite to decrea...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Blackwell Science Inc
2004
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884440/ https://ncbi.nlm.nih.gov/pubmed/14748816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01988.x |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|