Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men

AIMS: The influence of ageing on the pharmacokinetics of zolpidem, an extensively prescribed hypnotic medication, was evaluated in healthy human volunteers. METHODS: A series of 16 elderly (age: 61–85 years) and 24 young (age: 22–42 years) volunteers received single 5 mg oral doses of zolpidem tartr...

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Autors principals: Olubodun, Joel O, Ochs, Hermann R, von Moltke, Lisa L, Roubenoff, Ronenn, Hesse, Leah M, Harmatz, Jerold S, Shader, Richard I, Greenblatt, David J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
Matèries:
Pharmacokinetics and Drug Disposition
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884349/
https://ncbi.nlm.nih.gov/pubmed/12919178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2003.01852.x
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