Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients

AIMS: This analysis was performed to investigate the population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients using a nonlinear mixed effects modelling approach. METHODS: One thousand five hundred and forty-six acute stroke patients (774...

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Bibliographic Details
Main Authors: Zingmark, Per-Henrik, Ekblom, Marianne, Odergren, Tomas, Ashwood, Tim, Lyden, Patrick, Karlsson, Mats O, Jonsson, E Niclas
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884288/
https://ncbi.nlm.nih.gov/pubmed/12895190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2003.01850.x
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