Loading...

The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites

1. A single dose of clomethiazole (600 μmol kg(−1) i.p.) has previously been shown to be neuroprotective in the gerbil model of global ischaemia. 2. In gerbils, clomethiazole (600 μmol kg(−1)) injection produced a rapid appearance (peak within 5 min) of drug in plasma and brain and similar clearance...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Green, A R, Murray, T K, Misra, A, Snape, M F, Jones, J A, Cross, A J
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621131/
https://ncbi.nlm.nih.gov/pubmed/10694207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703042
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!