Simulation of amoxicillin pharmacokinetics in humans for the prevention of streptococcal endocarditis in rats.

The pharmacokinetic determinants of successful antibiotic prophylaxis of endocarditis are not precisely known. Differences in half-lives of antibiotics between animals and humans preclude extrapolation of animal results to human situations. To overcome this limitation, we have mimicked in rats the a...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Fluckiger, U, Moreillon, P, Blaser, J, Bickle, M, Glauser, M P, Francioli, P
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1994
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2846
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