Simulation of amoxicillin pharmacokinetics in humans for the prevention of streptococcal endocarditis in rats.
The pharmacokinetic determinants of successful antibiotic prophylaxis of endocarditis are not precisely known. Differences in half-lives of antibiotics between animals and humans preclude extrapolation of animal results to human situations. To overcome this limitation, we have mimicked in rats the a...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2846 |
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