Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis.

Inhibition constants were determined for 16 nucleoside analog triphosphates against human DNA polymerases alpha, beta, gamma, and epsilon, and 7 nucleoside analogs were examined as inhibitors of mitochondrial DNA synthesis in human Molt-4 cells in culture. The results demonstrate no clear quantitati...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Martin, J L, Brown, C E, Matthews-Davis, N, Reardon, J E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.12.2743
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