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Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis.

Inhibition constants were determined for 16 nucleoside analog triphosphates against human DNA polymerases alpha, beta, gamma, and epsilon, and 7 nucleoside analogs were examined as inhibitors of mitochondrial DNA synthesis in human Molt-4 cells in culture. The results demonstrate no clear quantitati...

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Detalhes bibliográficos
Main Authors: Martin, J L, Brown, C E, Matthews-Davis, N, Reardon, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188279/
https://ncbi.nlm.nih.gov/pubmed/7695256
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