Effect of ketoconazole on lethal action of amphotericin B on Leishmania mexicana promastigotes.

The effect of ergosterol depletion by ketoconazole on the leishmanicidal activity of the pore-forming antibiotic amphotericin B (AmB) was investigated. Leishmania mexicana promastigotes were lysed within minutes by the addition of micromolar concentrations of AmB (0.5 microM) but became insensitive...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ramos, H, Saint-Pierre-Chazalet, M, Bolard, J, Cohen, B E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188153/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8067741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.5.1079
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