Activity of a Heat-Induced Reformulation of Amphotericin B Deoxycholate (Fungizone) against Leishmania donovani

The heat treatment of amphotericin B deoxycholate (Fungizone), which was previously shown to induce superaggregation and decrease the toxicity of the drug to mammalian cells, increased its activity against Leishmania donovani in BALB/c mice, whereas it reduced its toxicity. Heat treatment preserved...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Petit, C., Yardley, V., Gaboriau, F., Bolard, J., Croft, S. L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Susceptibility
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.390
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