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Effect of ketoconazole on lethal action of amphotericin B on Leishmania mexicana promastigotes.

The effect of ergosterol depletion by ketoconazole on the leishmanicidal activity of the pore-forming antibiotic amphotericin B (AmB) was investigated. Leishmania mexicana promastigotes were lysed within minutes by the addition of micromolar concentrations of AmB (0.5 microM) but became insensitive...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: Ramos, H, Saint-Pierre-Chazalet, M, Bolard, J, Cohen, B E
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1994
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8067741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.5.1079
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