High specificity of cphA-encoded metallo-beta-lactamase from Aeromonas hydrophila AE036 for carbapenems and its contribution to beta-lactam resistance.

The Aeromonas hydrophila AE036 chromosome contains a cphA gene encoding a metallo-beta-lactamase highly active against carbapenem antibiotics. This enzyme was induced in strain AE036 to the same extent by both benzylpenicillin and imipenem. When the cphA gene was inserted into plasmid pACYC184, used...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Segatore, B, Massidda, O, Satta, G, Setacci, D, Amicosante, G
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1993
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8328781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1324
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